Lurker > StealThisSheen

But he was literally about to dispose of 17 and did dispose of Frieza, who was only saved by 17 rock throwing antics
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CelesMyUserName posted...

Basically it would've been great if Toppo's GoD power... accomplished anything. We watched him still failing to deal with the likes of Frieza and 17, and he was just pretty well clowned by SSB2 Vegeta and didn't put much of a fight at all

literally dyspo accomplished more than toppo lmao

wut

It was very clear Toppo would've beaten 17/Frieza
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I don't remember Tatsu being such an incredible actor
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...Yes. Yes.

Somebody do this.

Yes.
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Sorry guys, you are incorrect

I now can't wait for Teenage Mutant Ninja Raphaels
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It's sad, 'cuz Sony was given the option to allow cross-play with Xbone and Switch on this, Minecraft, and a few other things, and Sony basically went "No, fuck you guys"
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Xiahou Shake posted...

KCF0107 posted...

I would play Rocket League if you had it for a different system...

I'm super confused about what the state of Rocket League crossplay is right now. Back in the day, it was that PC and PS4 could play with each other, but now I'm seeing that basically everyone except PS4 can play together? Did they remove the PC/PS4 play, or is it some bizarre thing where PC can play with everyone but others can only play with certain other consoles? How does that even play out in matchmaking? >_>

Sony are bitches about crossplay with other systems, so as far as I know, and somebody correct me if I'm wrong...

PS4/PC can cross-play (unless this changed)
Switch/Xbone/PC can cross-play

PS4 and Switch or Xbone cannot cross-play.
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...Actually, guys. I may be being a bit hasty, here.

It doesn't actually say Raph is going to act like Leo. It only says Leo is going to act like Raph.

What if there's just going to be two Raphs.

This may actually be an improvement!
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The personalities are the most important thing!

Raphael is cool but rude
Leonardo is the level-headed leader. Level. L. Leader. L. Leo. L. It's science.
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Nah the CG show was actually good

The CG show got canceled for this
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swordz9 posted...

Why is April flying a bike that is connected to Donnies shoulders?

Because he's a soft-shell turtle and thus wears a fake shell or shell cover or something that is built with TECHNOLOGY, apparently.
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Anagram posted...

But I thought Leonardo leads and Raphael is cool but rude?

Is Donatello now a party dude?

Thankfully no. Donatello and Mikey remain unchanged.
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TheRock1525 posted...

The personality thing is new to me, where'd you hear that?

The descriptions of the characters.

Leonardo: Leonardo (Ben Schwartz) is a red-eared slider who boasts irreverent charm and a rebel heart. Weapon of choice: dachi sword.

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Actually, that post is inaccurate. They did say Raph was gonna be leader before. They just never said they were outright flipping his/Leo's personalities.
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They switched Leo and Raph's roles

And thus broke everything that was once good
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Raphael (Omar Miller) is now the leader and oldest brother, a snapping turtle who brandishes twin tonfas as his weapons.

What have they done
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Seplito Nash, Smelling Like the Vault since 1996
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Bob Roode better be ready
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DeepsPraw posted...

Assuming that there is somehow "medium dogs" is stupid. You take what the question gives you

This question is only bad because of half dogs

Well, the assumption of "medium dogs" would typically only come from realizing you can't have a whole number amount of small and large dogs without some type of third dog. So "half dogs" directly leads to the potential of "medium dogs."
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Baby Driver
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House Speaker Paul Ryan responded in a news conference Thursday by defending House Intelligence Chairman Devin Nunes and supporting the release of the committee's Republican memo that alleges abuses of the FISA surveillance law. He said the Nunes memo "does not impugn the Mueller investigation or the deputy attorney general," Rod Rosenstein.
"Congress doing its job in conducting legitimate oversight over a very unique law, FISA, and if mistakes were made and if individuals did something wrong then it is our job as the legislative branch of government to conduct oversight over the executive branch if abuses were made," Ryan said. "What this is not is an indictment on our institutions of our justice system. This memo is not an indictment of the FBI, of the Department of Justice."
Ryan dismissed the calls to remove Nunes as chairman, saying Democrats were "playing politics."

https://www.cnn.com/2018/02/01/politics/schumer-pelosi-paul-ryan-nunes-memo/index.html
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HaRRicH posted...

Has there been a response from Ryan regarding Pelosi and Schumer targeting him in their statements? NPR said Ryan's doubling down with Nunes, but I can't tell if they meant before today or after their statements today.

He said they're just playing political games. Lemme find a source.
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So maybe somebody here knows

On what grounds are House Republicans refusing to allow the Senate Intelligence Committee to see the memo? Like, have they given a reason?
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Grand Kirby posted...

Amusingly enough, that Arbok didn't die
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Yeah, it's just lights and brights
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ChampionCloud posted...

Weavile, Drapiion, Meowth and Mewtwo have all been killed in battle (or at least by Pokmon attacks). [and now Snorlax].

In addition to that, Yveital straight murder like 20 Pokmon and humans with Oblivion Wing, but Xerneas revives them at end of film.

So then the answer is "No, it hasn't happened. I'm just being MWC."

Gotcha.
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Leafeon13N posted...

Nah double heroic sacrifice.

Yeah, the reason I discount heroic sacrifice is because it's not typically an actually violent death. Heroic sacrifice and showing a Pokemon actually killing another in battle seem like two different beasts to me.
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StealThisSheen posted...

Leafeon13N posted...

At least two have died by movie 8.

Don't know about in episodes though. I'm sure more have died in movies beyond.

Are we talking like, legitimate death from battle/wounds/etc. that they didn't return from, or are we talking like, "I used all my energy and now I'm fading away" legendary stuff.

Let me append on to this a little more.

I mean like, legitimately died, on-screen, in battle. As in literally killed by another Pokemon straight up, no doubt, confirmed death. Not counting stuff like the "heroic sacrifice" stuff with Lucario and such, and apparently there's an episode where a Stoutland dies of old age.
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Leafeon13N posted...

At least two have died by movie 8.

Don't know about in episodes though. I'm sure more have died in movies beyond.

Are we talking like, legitimate death from battle/wounds/etc. that they didn't return from, or are we talking like, "I used all my energy and now I'm fading away" legendary stuff.
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Pirateking2000 posted...

Comedic deflation

Also this

If that was supposed to be Snorlax legitimately dying, they wouldn't have him comically deflating like a balloon
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ChampionCloud posted...

StealThisSheen posted...

ChampionCloud posted...

StealThisSheen posted...

ChampionCloud posted...

SantaRPidgey posted...

wait, did snorlax just legit die

YUP

I highly, highly doubt this

Please feel free to explain how it wouod survive that....

Same way Pokemon survive being electrocuted and burned and drowned and crushed and blown up and popped and sliced and a million other things

It's an anime aimed at kids

So is Dragonball....

Name all the times Pokemon have legitimately died on screen in battles in the Pokemon anime
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ChampionCloud posted...

StealThisSheen posted...

ChampionCloud posted...

SantaRPidgey posted...

wait, did snorlax just legit die

YUP

I highly, highly doubt this

Please feel free to explain how it wouod survive that....

Same way Pokemon survive being electrocuted and burned and drowned and crushed and blown up and popped and sliced and a million other things

It's an anime aimed at kids
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ChampionCloud posted...

SantaRPidgey posted...

wait, did snorlax just legit die

YUP

I highly, highly doubt this
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You don't even really have to be sensitive to bright lights for it to bother you.

I think a lot of people don't realize that brights/high beams blind cars in front of you just as much as cars coming the other direction, if not moreso
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MrGreenonion posted...

HaRRicH posted...

I tend to keep mine on high beams since the closest cars to me are facing the same way

Yeah and then your beams reflect in the mirrors of the cars in front of you and you blind the drivers.

Don't be a dick. High beams off unless you specifically need them, are the lead car, and have no oncoming traffic.

Yeah, high beams are bad
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Basically, the issue isn't that they couldn't do the math. The issue was that the words used for that math problem are very likely to confuse somebody since you end up with half dogs, which logically isn't possible. If it was like, pizzas, then things would be different.
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NFUN posted...

Dancedreamer posted...

I mean technically the answer should be "Not enough information". Because there could be medium sized dogs. 3 medium sized dogs, 41 small dogs, and 5 large dogs works.

ill give you this pedantry for the random daily mail pictures but not for a 7 year old's math question

Well, the alternative is having half dogs, so...
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JONALEON1 posted...

Grand Kirby posted...

Oh boy, can't wait to pay 20$ a year for balloon fight.

I would be grateful if we got Balloon Fight. We're gonna get Urban Champion.

They've already advertised Balloon Fight, so...
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OliviaTremor posted...

StealThisSheen posted...

OliviaTremor posted...

StealThisSheen posted...

The brain simply doesn't work like that, anyway. You're not gonna go from "Never a depressed thought" to suicide after two doses of anything.

Oh oh! I'm a PhD candidate in neuroscience who has taught graduate level drug discovery courses and feel qualified in telling you that you are incredibly incorrect! Yay!

Care to explain?

Unless you're referring to drugs outside of pharmaceuticals and/or drugs specifically designed to do such a thing as treatment.

I have a very hard time believing that a drug with such a drastic side effect in two approved doses could pass testing/be approved for consumer sale.

Sure. Sorry if my post seemed condescending.

Let's look at Tamiflu, a Neuraminidase inhibitor. This viral protein isn't expressed within humans, making it a good druggable target with drastically limited off target effects. However, there are genes/proteins within the human genome with some sequences which are homologous for the most part. Now, each person's genome is unique and contains plenty of single nucleotide polymorphisms, or mutations, scattered throughout. Some of these are deleterious, such as for example the APC(min) mutation which is a single mutation in a single gene that predisposes you to colorectal cancer. Now, it is very possible that there exists humans with a single nucleotide polymorphism which disrupts a crucial protein, creating an active binding site for the drug Tamiflu where there shouldn't be. There are human neuramidase's and it is possible some people have SNPs allowing Tamiflu to bind when it shouldn't, thus these human neuramidase's no longer function properly. If this protein is normally expressed within specific neuronal subtypes critical for cognitive function, and it is no lunger working, it is possible cognitive function will be heavily impaired. This is one of the reasons why some people have different side effects than others. You can get more into it, involving how each person has different levels of proteins and stuff, but this is probably the most straightforward explanation.

The reason you probably won't see stuff like this until clinical trials or the drug is on the market is because for FDA approval you need to test it in a mammalian model-- typically a mouse. You might test it in 100 mice with varying efficacy, but each mouse is on the same background (ie tightly regulated and controlled so that their genome is close to identical, think of a family from the UK vs a family from Thailand).

All that said, I doubt Tamiflu was responsible for the person's death but who knows. Suicide is an intense subject with so many factors.

Thanks for the detailed response!

Yeah, I understand there are obviously things you can't account for, and I admitted that speaking in absolutes was a mistake. I was speaking moreso in general that... Presence of A doesn't automatically mean Condition B, and that there are often contributing factors to that. The brain itself isn't hardcoded to go

if itemA.contains(chemicalB) {
radicalSideEffectC = true
}

in most cases. Now, obviously, that's not to say something can't cause it to be, as you say. My argument was moreso an argument of... Other factors should be considered before just instantly jumping to "Tamiflu did it!"
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I think there could be money in having a wedding videography business where they can swap the spouse of their choice with Nic Cage
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I wanna use this to undo the face off in Face/Off
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I...

I have never been so happy

This is truly the peak of technology
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HotDogButts posted...

StealThisSheen posted...

The brain simply doesn't work like that, anyway. You're not gonna go from "Never a depressed thought" to suicide after two doses of anything. For that radical of a change, it'd require either an overdose or long-time dependency. The most it can do in normal circumstances is amplify feelings/thoughts that are already there.

Bruh people can eat gluten and get depressed because of it. It's not by any means a stretch for this to transpire. Whether it caused it or not, who knows, but saying "the brain simply doesn't work like that" is an overconfident statement, to say the least.

It was perhaps a poor word choice

What I mean to say is that dosage is typically at levels that are too low to cause more severe side effects without some other underlying factor. When I say "the brain doesn't work that way," I mean that the brain doesn't go "This thing has X in it that can cause depression, and you took it? Boom, I'm instantly massively, brokenly depressed!" That's not to say it can't happen, I'm merely saying... It's not like a boolean. It's not as if the brain has coding that goes:

if chemical == true {
depression = max
} else {
depression = 0
}

I'm trying to say that just because a side effect is listed, that doesn't automatically mean it's going to happen if you follow dosing correctly. And it's going to be extremely rare for such a thing to happen without other factors, such as overdosage, extended use, and so on.

I shouldn't have spoken in absolutes, my bad. My point is moreso that the likelihood of such a massive change happening after two correct doses is so small that it shouldn't be something one jumps to as the cause.
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OliviaTremor posted...

StealThisSheen posted...

The brain simply doesn't work like that, anyway. You're not gonna go from "Never a depressed thought" to suicide after two doses of anything.

Oh oh! I'm a PhD candidate in neuroscience who has taught graduate level drug discovery courses and feel qualified in telling you that you are incredibly incorrect! Yay!

Care to explain?

Unless you're referring to drugs outside of pharmaceuticals and/or drugs specifically designed to do such a thing as treatment.
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Celine
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I bought Knack when it was $4 and played it once and noooo thanks
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The brain simply doesn't work like that, anyway. You're not gonna go from "Never a depressed thought" to suicide after two doses of anything. For that radical of a change, it'd require either an overdose or long-time dependency. The most it can do in normal circumstances is amplify feelings/thoughts that are already there.
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Gatarix posted...

paperwarior posted...

The side effects are stated to include some psychological impact, just not to this extent.

StealThisSheen posted...

Two doses ain't gonna cause it unless they were well over the dosage limit, or he was suicidal/depressed already.

yeah see this was my initial reaction, but if that were the case, why not just deny fault? the fact that the Tamiflu spokesperson is hedging so much makes me wonder if there's actually merit behind the parents' theory

He can't deny it because it's already a listed side effect. It'd be like the makers of Cinnamon Toast Crunch going "You know what... There's not cinnamon and sugar swirls in every bite, after all."
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Ginyu's just loyal to a fault. The whole bunch seems like they'd have been pretty chill if they worked for somebody different.
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Two doses ain't gonna cause it unless they were well over the dosage limit, or he was suicidal/depressed already.
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SantaRPidgey posted...

I don't have any degree.

Do I need one to point out how stupid comparing consuming water to literally any other chemical on earth is colossally intellectually dishonest?

This kind of attitude is why idiots die in things like "Hold your wee for a Wii" contests.
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