Poll of the Day > Disturbing New Pfizer Vaccine Study

(+) Yeah! (+)

blah blah blah

blah blah blah

Conservatives so desperately want people to die from the shots so they can say "lol i told you so"

Sad

What is disturbing

Furthermore, they demand extra studies (like the one linked) but when they don't give the conclusion they want they somehow ignore it

So it's a bad thing to study the effects of a vaccine type that's never been used before, and has absolutely no long term data?

I posted [bad faith] and you [insult]s...

I posted a study that shows there's a potential for an autoimmune disorder, and look at how you defectives respond. I think you just see completely different words when you read something.

• Conversion of RNA into DNA in the cells
• The quantity of a genetic tool called LINE-1
• The presence of DNA sequences similar to the vaccine RNA in the nuclei of these cells

1. Perhaps most importantly, this experiment was done on cells being grown in a lab. Said another way, it was an in vitro experiment. In vitro experiments are done all the time and they are important for providing information and clues as to what might happen in a person (in vivo). However, to make a conclusion about what is happening in people, one must have some evidence that it is actually happening in people, not just that it might be possible. The authors acknowledged this when they wrote, At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome. Further studies are needed (p. 1122). They go on to suggest two alternative experimental methods for getting more information.
2. The authors used a cancerous liver cell line. This is important for two reasons; both of which were acknowledged by the authors. First, cancerous cell lines replicate, whereas our liver cells typically are not replicating. As such, even if DNA representing the viral RNA was integrated into the cell, no other cells with the altered DNA would be produced. The authors also pointed out that this cell line has been shown to have genetic and protein expression differences specific to RNA metabolism (p. 1123). This means that what is seen in these cells may not be representative of what would happen in non-cancerous liver cells (or even a different line of cancerous liver cells). Second, they measured LINE-1 activity. Importantly, LINE-1 has been associated with various disease-related conditions, including cancer. It has also been shown to affect immune responses. For these reasons, while the changes related to LINE-1 are interesting, we cant be sure the effects would be the same in a non-cancerous cell line. The authors also made this point by stating, The exact regulation of LINE-1 activity in response to BNT162b2 merits further study. (p. 1123).
3. Finally, as the authors pointed out, expression of LINE-1 has been shown to increase during viral infections, including with SARS-CoV-2 virus. In fact, some scientists have suggested that integration of SARS-CoV-2 genetic material into human cells could be why some people still test positive by PCR well after they have recovered from their infection. However, it is important to note that more information would be needed to prove this hypothesis as well. The more likely explanation is that the virus is undergoing an incomplete cycle of replication, where the genetic material (RNA) is produced but whole virus particles are not.

Glad I got the J&J.

You know why you posted it, it didn't have the effect you thought because people have good sense and aren't ruffled by possibilities - especially when posted in bad faith

You jumping to insults is doubly revealing in case anyone doubted your bad faith

Jumping to insults? Did you not notice the dozen or so posts directing insults at me first?

hey dude. in science fields, criticism = constant and is part of the job. don't crap your panties and call everyone defective for holding you accountable with a very basic discussion. Your interpretation is dramatic and not does not indicate the same concerns as the studies conclusion.

Nobody likes you here dude. And nobody cares about anything you post.

That's not the same study. Did you think I wouldn't notice?

Whoa, are you accusing Ozmose of saying something stupid?!

You know what? I think I'm just going to give back the same as I usually get.

You know what? I think I'm just going to give back the same as I usually get.