Current Events > Don't it normally take years to develop a vaccine?

(+) Yeah! (+)

How come there are reports about vaccines being developed by the end of the year or by early 2021? Nobody find that sketchy?

I ain't an anti-vaxxer but you can't tell me that ain't fishy.

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There's a fuckton of middlemen and regulators in the way.
That's why.

I'd imagine that given the severity of the pandemic that FAR more resources have been put into the development of this vaccine as opposed to other vaccines.

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Shadow Don posted...

I'd imagine that given the severity of the pandemic that FAR more resources have been put into the development of this vaccine as opposed to other vaccines.

This.

All over the world there are massive numbers of people working on nothing else and getting tons of funding veto do whats typically available.

Not sure why youd find this sketchy.

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the vaccines being financed by the federal government use a completely different method of production and function compared to traditional vaccines.

traditional vaccines take so long because it takes a very long time to develop the correct methods to disable the virus in such a way that it produces antigenic material but isn't infectious. then they have to be incubated (often in chicken eggs) to produce large quantities of the vaccine.

the new method that's being pushed is an RNA vaccine. the idea is that instead of dealing with dead/attenuated virus you produce RNA that code for the antigenic sites. in simple terms, RNA acts as a blueprint molecule for your cells (in this case immune cells) to produce proteins, the RNA developed code for those antigens that should produce a strong antibody response. doing it this way potentially cuts out months/years of vaccine development, but there's never been a successful RNA vaccine used on humans.

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monkmith posted...

there's never been a successful RNA vaccine used on humans.

Interesting. Have they used one on animals/ livestock?

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monkmith posted...

in simple terms, RNA acts as a blueprint molecule for your cells (in this case immune cells) to produce proteins

This is either the plot to a really bad movie, or a really pretentious video game.

Jabodie posted...

Interesting. Have they used one on animals/ livestock?

yes. if i'm not mistaken there's a RNA vaccine used for some rabies vaccines for pets, there are others but i cant think of any off the top of my head.

keep in mind, vaccines that work in animal analogues, even something like a modified SCID mouse that's supposed to have a 'human like immune system' will often show false positive results for testing things like this.

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There is a lot of funding. And some researchers even stopped their AIDS and cancer research to focus on a coronavirus vaccine.

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Lebronwon posted...

There is a lot of funding. And some researchers even stopped their AIDS and cancer research to focus on a coronavirus vaccine.

sure, but what irritates me is that the sum total of federal funding is going to unproven vaccine production methods, all because they have the potential to be the quickest.

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monkmith posted...

the vaccines being financed by the federal government use a completely different method of production and function compared to traditional vaccines.

traditional vaccines take so long because it takes a very long time to develop the correct methods to disable the virus in such a way that it produces antigenic material but isn't infectious. then they have to be incubated (often in chicken eggs) to produce large quantities of the vaccine.

the new method that's being pushed is an RNA vaccine. the idea is that instead of dealing with dead/attenuated virus you produce RNA that code for the antigenic sites. in simple terms, RNA acts as a blueprint molecule for your cells (in this case immune cells) to produce proteins, the RNA developed code for those antigens that should produce a strong antibody response. doing it this way potentially cuts out months/years of vaccine development, but there's never been a successful RNA vaccine used on humans.

An interesting read, thank you for sharing! Is there anywhere I could learn more about this?
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monkmith posted...

sure, but what irritates me is that the sum total of federal funding is going to unproven vaccine production methods, all because they have the potential to be the quickest.

Agreed. US is stuck with 63 million doses of hydroxychloroquine.

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