Current Events > people are such morons when it comes to science

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DarkRoast
12/23/18 11:48:57 AM
#51:


COVxy posted...
DarkRoast posted...
It's not clear if they're referring to in utero use or post-birth exposure.


That doesn't really matter, if they observed effects of gene methylation in children it would indeed be potentially an important finding, either way.


Unfortunately for both of us it seems to be point mutation rate.
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Kombucha
12/23/18 11:49:23 AM
#52:


fetus don't actually have dna, that would imply they have a soul and i do not believe in jesus.
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COVxy
12/23/18 11:50:07 AM
#53:


DarkRoast posted...
COVxy posted...
DarkRoast posted...
It's not clear if they're referring to in utero use or post-birth exposure.


That doesn't really matter, if they observed effects of gene methylation in children it would indeed be potentially an important finding, either way.


Unfortunately for both of us it seems to be point mutation rate.


This is true, but like I said, no matter what the article actually says, it was a silly thing for you to post. My guess is that you just misread the OP, but you double downed on it.
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DarkRoast
12/23/18 11:51:48 AM
#54:


To be fair, were talking about a source interpreted by DailyMail UK
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Banana_Cyanide
12/23/18 11:53:20 AM
#55:


I like how COVxy and DarkRoast are legitimately arguing over the study while everyone else is trolling with stereotypical religious rhetoric.
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MarqueeSeries
12/23/18 11:55:35 AM
#56:


Banana_Cyanide posted...
I like how COVxy and DarkRoast are legitimately arguing over the study while everyone else is trolling with stereotypical religious rhetoric.

Best to leave them to their specialization and us to ours
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DaveTheUseless
12/23/18 11:56:37 AM
#57:


Uhm, I'm pretty sure evolution is just a theory.
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Kombucha
12/23/18 11:57:15 AM
#58:


MarqueeSeries posted...
Banana_Cyanide posted...
I like how COVxy and DarkRoast are legitimately arguing over the study while everyone else is trolling with stereotypical religious rhetoric.

Best to leave them to their specialization and us to ours


Don't worry, I sometimes waft my own farts as well.
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DarkRoast
12/23/18 11:59:20 AM
#59:


Kombucha posted...
MarqueeSeries posted...
Banana_Cyanide posted...
I like how COVxy and DarkRoast are legitimately arguing over the study while everyone else is trolling with stereotypical religious rhetoric.

Best to leave them to their specialization and us to ours


Don't worry, I sometimes waft my own farts as well.


You're not legit until you taste it
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Romes187
12/23/18 12:26:04 PM
#60:


Weed kills the weak sperm and allows only the strongest to survive

That way if your money shot is front loaded heavily with knucklehead sperm, they cant get lucky by having a better spot in line.

Time to start the high master race
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Kineth
12/24/18 1:51:36 AM
#61:


COVxy posted...
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.


This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.


It's actually a salient point.
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COVxy
12/24/18 7:14:26 AM
#62:


Kineth posted...
COVxy posted...
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.


This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.


It's actually a salient point.


You bumped a dead topic to comment on a post while ignoring all the subsequent discussion on said post?
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Kineth
12/24/18 7:36:26 AM
#63:


COVxy posted...
Kineth posted...
COVxy posted...
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.


This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.


It's actually a salient point.


You bumped a dead topic to comment on a post while ignoring all the subsequent discussion on said post?


It popped up in the "More topics from this board.." thing and molecular genetics is my jam.

That said, I didn't really have much time to read the article in the first place, but my cursory glance of the topic made me lose interest in the other parts since there was a lot of drama over Coffeebeanz and not much discussion of the biochemistry.
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COVxy
12/24/18 7:39:56 AM
#64:


Changes in methylation are biologically important, full stop. It's silly to wave off changes in methylation. That's the point I was making.
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DarkRoast
12/24/18 7:42:48 AM
#65:


COVxy posted...
Changes in methylation are biologically important, full stop. It's silly to wave off changes in methylation. That's the point I was making.


And I said the effects of inherited epigenetic changes on offspring are debatable, and provided a source. Not exactly sure why that caused drama.
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COVxy
12/24/18 7:46:37 AM
#66:


DarkRoast posted...
COVxy posted...
Changes in methylation are biologically important, full stop. It's silly to wave off changes in methylation. That's the point I was making.


And I said the effects of inherited epigenetic changes on offspring are debatable, and provided a source. Not exactly sure why that caused drama.


You either misread the OP and doubled down on it, or are just being silly.

Based on the OP, this wouldn't haven't very much direct relation to inheritance of epigenetic effects. It certainly could, but that would be a stupid fucking reading of it because inheritance of epigenetic changes is rare at best, with no evidence in humans.

The OP makes it clear that changes were observed in the children, not the parents. If it said "gene changes in parents potentially leading to harm in offspring" your comment would have been reasonable.
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Kombucha
12/24/18 7:48:50 AM
#67:


There can only be one scully.
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Kineth
12/24/18 7:57:36 AM
#68:


COVxy posted...
Changes in methylation are biologically important, full stop. It's silly to wave off changes in methylation. That's the point I was making.


Yeah, I understand that. Methylation and other such types of modifications are generally for changes in structure and gene access. Shutting off or turning on genes in this way is generally temporary.

It's a salient point to say that methylation isn't as bad as genetic mutations and shifting bases, etc. etc. If your issue is that you thought it was being completely dismissive, I can understand that, but you've gotta understand that methylation of DNA happens regularly.

That said, I'm a little rusty on my knowledge on the various types of modifications like this. I know that some are actually bad, but you only spent time haranguing her over that that I still haven't gotten the info on why methylation of DNA is so fucking devastating and if it's targeting specific genes.
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COVxy
12/24/18 8:06:27 AM
#69:


Kineth posted...
It's a salient point to say that methylation isn't as bad as genetic mutations and shifting bases, etc. etc. If your issue is that you thought it was being completely dismissive, I can understand that, but you've gotta understand that methylation of DNA happens regularly.


The point is that it happens regularly. Gene methylation mediates a lot of normal biological function, and therefore changes in it can lead to a lot of changes to normal functioning. I'm not over here arguing one is "worse" than the other (highly context dependent, as both can simply part of normal functioning). Just that waving off observed changes in methylation is silly.
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DarkRoast
12/24/18 8:07:30 AM
#70:


COVxy posted...
Kineth posted...
It's a salient point to say that methylation isn't as bad as genetic mutations and shifting bases, etc. etc. If your issue is that you thought it was being completely dismissive, I can understand that, but you've gotta understand that methylation of DNA happens regularly.


The point is that it happens regularly. Gene methylation mediates a lot of normal biological function, and therefore changes in it can lead to a lot of changes to normal functioning. I'm not over here arguing one is "worse" than the other (highly context dependent, as both can simply part of normal functioning). Just that waving off observed changes in methylation is silly.


Nobody waved it off jfc
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COVxy
12/24/18 8:11:24 AM
#71:


DarkRoast posted...
Nobody waved it off jfc


Either you were arguing that it's unimportant because inheritance is debatable, or you didn't wave it off. One or the other, not both. Choose one.
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DarkRoast
12/24/18 8:11:57 AM
#72:


COVxy posted...
DarkRoast posted...
Nobody waved it off jfc


Either you were arguing that it's unimportant because inheritance is debatable, or you didn't wave it off. One or the other, not both. Choose one.


Do you even know what the word significance means?
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COVxy
12/24/18 8:24:33 AM
#73:


DarkRoast posted...
COVxy posted...
DarkRoast posted...
Nobody waved it off jfc


Either you were arguing that it's unimportant because inheritance is debatable, or you didn't wave it off. One or the other, not both. Choose one.


Do you even know what the word significance means?


No technical definition in this sense, so in the normal, importance.
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