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Fam_Fam 12/23/18 8:17:39 AM #1: |
I go on FB, and there's a study that found that marijuana use affected the DNA of children of users, and that more use correlated with larger changes in DNA.
A bunch of people just posted "bullshit", so I asked what issues they had with the methodology of the study, or what evidence they had to the contrary. The response i got was essentially "A ton of people, including myself, used marijuana and had positive benefits, and it was recommended to us by doctors. Also, all of our children turned out fine". And I'm like, none of that refutes the study results at all, and none of that is actual evidence of anything that would suggest that the results are wrong. People somehow thing that a story of their amazing kids somehow is evidence that there are no possible side effects, and that scientific evidence is "bullshit" when it doesn't agree with their own narrative (which is based in their "experience" with marijuana, and with no actual scientific evidence). ... Copied to Clipboard!
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glitteringfairy 12/23/18 8:18:46 AM #2: |
People in general are morons
--- "How come you can believe in God but not Bigfoot?" V-E-G-Y https://imgur.com/AqR3aeX https://imgur.com/vvuUXpp https://imgur.com/r9xK2NR ... Copied to Clipboard!
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Kombucha 12/23/18 8:28:49 AM #3: |
I used to think maybe the west was in the process of abandoning the scientific method and all of the great advances that came with the renaissance.
I realized I had been sheltered though and only a portion of the elite really cared about finding the truth. It's almost always been this way- the masses have almost always been fucking morons that prefer convenient hearsay and mysticism. Now that we've democratized speech with the internet it's just becoming even more obvious. Do you remember when Facebook was university only? Pepperidge farm remembers. --- ... Copied to Clipboard!
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teepan95 12/23/18 8:31:04 AM #4: |
glitteringfairy posted...
People in general are morons --- I use Gameraven and you should too. http://error1355.com/ce/teepan95.html ... Copied to Clipboard!
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PrettyBoyFloyd 12/23/18 8:32:15 AM #5: |
Honestly I don't know how to do the math to figure out how to break down a Time Continual or create a Wormhole to travel around all of God's creation.
--- The Evil Republicans - Est.2004 - WoT [Government Destabilizing Branch] ... Copied to Clipboard!
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#6 | Post #6 was unavailable or deleted. |
CoolBro 12/23/18 8:38:54 AM #7: |
some people who dont go to stem ...they dont understand how research study works
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Dragon239 12/23/18 8:40:17 AM #8: |
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Kombucha 12/23/18 8:40:24 AM #9: |
JACKBUTTMOMMY posted...
Kombucha posted...I used to think maybe the west was in the process of abandoning the scientific method and all of the great advances that came with the renaissance. Depends on the institution & program, yeah. --- ... Copied to Clipboard!
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catboy0_0 12/23/18 8:40:43 AM #10: |
yah.. I'm not reading that shit
--- I obviously like you at least a little to even talk to you -cornman one day I hope to post a message so great it ends up in someones sig -Two_Dee ... Copied to Clipboard!
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DarkRoast 12/23/18 8:40:44 AM #11: |
If this is related to methylation and not mutation rate, the actual significance is debatable.
--- Well allons-y, Alonso! ... Copied to Clipboard!
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HydraSlayer82 12/23/18 8:50:16 AM #12: |
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable. Yeah, I was going to say changing DNA with on and off switches isnt necessarily good or bad. Plenty of useless code in our DNA. --- Sigless user ... Copied to Clipboard!
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Fam_Fam 12/23/18 9:23:21 AM #13: |
also, edit: the study was about the fertility and DNA of the men themselves, not their children. it said it was inconclusive if these mutations were passed on.
https://tinyurl.com/ycae4wg9 ... Copied to Clipboard!
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COVxy 12/23/18 9:27:05 AM #14: |
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable. This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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Banana_Cyanide 12/23/18 10:00:48 AM #15: |
COVxy posted...
This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish. Wait, you are an MD right? --- Who knew bananas could be so lethal? Proud member of The Church of The Man-Emperor of Mankind. ... Copied to Clipboard!
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NameMeWhatever 12/23/18 10:19:34 AM #16: |
Science is stupid made up bullshit worst than religion anyway, so who cares.
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HydraSlayer82 12/23/18 10:20:57 AM #17: |
NameMeWhatever posted...
Science is stupid made up bullshit worst than religion anyway, so who cares. 7 karma --- Sigless user ... Copied to Clipboard!
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Gafemage 12/23/18 10:36:42 AM #18: |
NameMeWhatever posted...
Science is stupid made up bullshit worst than religion anyway, so who cares. --- ... Copied to Clipboard!
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NameMeWhatever 12/23/18 10:39:01 AM #19: |
HydraSlayer82 posted...
NameMeWhatever posted...Science is stupid made up bullshit worst than religion anyway, so who cares. This isn't Reddit you plebian. How many "points" you have doesn't matter, it just shows you how much of your life you wasted. Science is the religion of man. It is putting your faith in man to tell you how the world around you works. Which is just as bad as putting your faith into a magical creator. ... Copied to Clipboard!
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Banana_Cyanide 12/23/18 10:40:54 AM #20: |
You're a special kind of edgy boi aren't you?
--- Who knew bananas could be so lethal? Proud member of The Church of The Man-Emperor of Mankind. ... Copied to Clipboard!
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soulunison2 12/23/18 10:43:53 AM #21: |
NameMeWhatever posted...
HydraSlayer82 posted...NameMeWhatever posted...Science is stupid made up bullshit worst than religion anyway, so who cares. Holy shit how sheltered are you Have you ever been shot at ... Copied to Clipboard!
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Kombucha 12/23/18 10:45:25 AM #22: |
soulunison2 posted...
NameMeWhatever posted...HydraSlayer82 posted...NameMeWhatever posted...Science is stupid made up bullshit worst than religion anyway, so who cares. ftfy --- ... Copied to Clipboard!
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MrPeppers 12/23/18 10:46:33 AM #23: |
The worst are college-educated individuals who know how to google studies and read abstracts, but aren't versed enough in analyzing the literature to actually parse through what's supportive and what's probably not supportive.
I honestly had no clue how to analyze a study until I was forced to through postgraduate training, and I suspect that most people with just undergraduate degrees have no clue what they're doing. --- ... Copied to Clipboard!
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soulunison2 12/23/18 10:55:10 AM #24: |
MrPeppers posted...
The worst are college-educated individuals who know how to google studies and read abstracts, but aren't versed enough in analyzing the literature to actually parse through what's supportive and what's probably not supportive. oh damn proudclad he's taking shots at you ... Copied to Clipboard!
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COVxy 12/23/18 10:58:38 AM #25: |
Banana_Cyanide posted...
COVxy posted...This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish. Naw. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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Banana_Cyanide 12/23/18 11:05:01 AM #26: |
COVxy posted...
Naw. I know someone on here is an MD but I can't remember who it is. --- Who knew bananas could be so lethal? Proud member of The Church of The Man-Emperor of Mankind. ... Copied to Clipboard!
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COVxy 12/23/18 11:06:46 AM #27: |
Banana_Cyanide posted...
COVxy posted...Naw. CoffeeBeanz is, which is who I was talking too. I'm in biomedical sciences broadly, but I'm finishing up my PhD in neuroscience. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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MrPeppers 12/23/18 11:07:06 AM #28: |
Banana_Cyanide posted...
COVxy posted...Naw. DarkRoast is an MD with training in internal medicine. COVxy is a PhD in neuroscience. --- ... Copied to Clipboard!
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COVxy 12/23/18 11:16:28 AM #29: |
MrPeppers posted...
The worst are college-educated individuals who know how to google studies and read abstracts, but aren't versed enough in analyzing the literature to actually parse through what's supportive and what's probably not supportive. Also, this is absolutely accurate. Unless the undergrad has had extensive training in a lab, which usually they haven't. It takes a couple of years before an undergrad trained in my current lab is reading the papers with any form of critical lens. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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Banana_Cyanide 12/23/18 11:17:50 AM #30: |
COVxy posted...
CoffeeBeanz is, which is who I was talking too. I just looked up the account and apparently it's closed. --- Who knew bananas could be so lethal? Proud member of The Church of The Man-Emperor of Mankind. ... Copied to Clipboard!
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Gafemage 12/23/18 11:19:30 AM #31: |
Banana_Cyanide posted...
COVxy posted...CoffeeBeanz is, which is who I was talking too. DarkRoast = CoffeeBeanz --- ... Copied to Clipboard!
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COVxy 12/23/18 11:19:36 AM #32: |
Banana_Cyanide posted...
COVxy posted...CoffeeBeanz is, which is who I was talking too. Yeah, she closed it and opened DarkRoast, afaik. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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Banana_Cyanide 12/23/18 11:21:46 AM #33: |
Gafemage posted...
DarkRoast = CoffeeBeanz That explains it. Well I tagged who I needed to so I'll know who to listen to in future topics. --- Who knew bananas could be so lethal? Proud member of The Church of The Man-Emperor of Mankind. ... Copied to Clipboard!
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DarkRoast 12/23/18 11:27:26 AM #34: |
COVxy posted...
DarkRoast posted...If this is related to methylation and not mutation rate, the actual significance is debatable. Cool rebuttal Asshole attitude not called for Here's my source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020004/ How epialleles arise in nature is still an open question but environmentally induced epigenetic changes are rarely transgenerationally inherited, let alone adaptive, even in plants. Thus, although much attention has been drawn to the potential implications of transgenerational inheritance for human health, so far there is little support. Your turn. --- Well allons-y, Alonso! ... Copied to Clipboard!
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COVxy 12/23/18 11:32:31 AM #35: |
DarkRoast posted...
COVxy posted...DarkRoast posted...If this is related to methylation and not mutation rate, the actual significance is debatable. A metric fuckton of biological function is mediated by methylation. Histone methylation is necessary for the formation of new memories. Synaptic maintenance in general. Seems incredibly silly, almost ill informed, to wave off methylation effects because they aren't direct mutations lol. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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DarkRoast 12/23/18 11:34:25 AM #36: |
COVxy posted...
DarkRoast posted...COVxy posted...DarkRoast posted...If this is related to methylation and not mutation rate, the actual significance is debatable. No, it isn't. As evidenced in my thing called a "source" Epigenetics is a highly debated field with not much good data one way or another. Hence "debatable". Hence you're being a pedantic asshole for seemingly no reason. --- Well allons-y, Alonso! ... Copied to Clipboard!
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ThePieReborn 12/23/18 11:35:11 AM #37: |
People are morons when it comes to everything.
--- Party leader, passive-aggressive doormat, pasta eater extraordinaire! ... Copied to Clipboard!
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COVxy 12/23/18 11:38:16 AM #38: |
DarkRoast posted...
COVxy posted...DarkRoast posted...COVxy posted...DarkRoast posted...If this is related to methylation and not mutation rate, the actual significance is debatable. Jesus fuck. The point wasn't regarding inheritance, there's a shit ton of biological pathways where drug use can affect off spring, you know. So the only one running off about necessity of inheritance of epigenetic effects is you. The OP referenced observed effects in the children, and you stated that if it's just methylation and not mutation, not necessarily something to write home about. Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes. I only know in depth about brain related ones, by my guess is that any system that depends on the regulation of protein production (which should be just about all of them) is going to heavily depend on methylation. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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DarkRoast 12/23/18 11:39:26 AM #39: |
Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes.
And the impact of this on offspring is hotly debated. Which is why I said "it's debatable". Quit arguing in circles just because you're so hot and bothered. --- Well allons-y, Alonso! ... Copied to Clipboard!
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COVxy 12/23/18 11:40:09 AM #40: |
DarkRoast posted...
Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes. This is about observed effects in children, not parents... --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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Kombucha 12/23/18 11:40:35 AM #41: |
wow i bet these nerds don't even blaze it how are they supposed to science the thc
--- ... Copied to Clipboard!
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Turtlebread 12/23/18 11:42:27 AM #42: |
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DarkRoast 12/23/18 11:43:09 AM #43: |
COVxy posted...
DarkRoast posted...Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes. Really? You sure know a lot about the article that TC hasn't even shown. --- Well allons-y, Alonso! ... Copied to Clipboard!
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COVxy 12/23/18 11:44:02 AM #44: |
DarkRoast posted...
Really? You sure know a lot about the article that TC hasn't even shown. I'm responding to the same information as you, which is: Fam_Fam posted... study that found that marijuana use affected the DNA of children of users, and that more use correlated with larger changes in DNA. Regardless as to what the study ACTUALLY says, your comment was silly. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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Fam_Fam 12/23/18 11:44:15 AM #45: |
DarkRoast posted...
COVxy posted...DarkRoast posted...Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes. i did post it, post 13. and made a correction about what the findings actually were ... Copied to Clipboard!
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DarkRoast 12/23/18 11:45:19 AM #46: |
COVxy posted...
DarkRoast posted...Really? You sure know a lot about the article that TC hasn't even shown. It's not clear if they're referring to in utero use or post-birth exposure. --- Well allons-y, Alonso! ... Copied to Clipboard!
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rikasa 12/23/18 11:46:18 AM #47: |
I'm sure that marijuana is way worse than most people realize but stoners don't want to hear the truth
--- you are not alone ... Copied to Clipboard!
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DarkRoast 12/23/18 11:47:27 AM #48: |
Here's his article:
https://www.dailymail.co.uk/health/article-6512173/Scientists-discover-cannabis-alters-DNA-sperm.html?ito=social-facebook In the first study of its kind, sperm samples were taken from healthy men - aged 18-to-40 - who claimed to use cannabis at least once a week for the past six months. These samples were compared against the sperm of 12 men who had not used cannabis in the past six months and had used it a maximum of ten times throughout their lives. Urine samples confirmed their marijuana use. Results supported past findings that cannabis users have significantly lower sperm concentrations than non-users When the DNA of the participants' sperm was analysed, the researchers found cannabis is linked to genetic changes. And the higher the amount of THC in the men's urine, the stronger the changes of carrying mutations were. It is unclear whether these changes influence a man's fertility or get passed on to his children - the affected sperm may not even be healthy enough to fertilise an egg. I'm not exactly impressed. They're also implying point mutations, it seems. Not epigenetics. --- Well allons-y, Alonso! ... Copied to Clipboard!
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DaveTheUseless 12/23/18 11:48:11 AM #49: |
Uhm pretty sure the world was created in 6 days
--- www.youtube.com/davetheuseless Creepypasta Channel. twitter.com/davetheuseless DaveTheUseless Loves You. ... Copied to Clipboard!
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COVxy 12/23/18 11:48:21 AM #50: |
DarkRoast posted...
It's not clear if they're referring to in utero use or post-birth exposure. That doesn't really matter, if they observed effects of gene methylation in children it would indeed be potentially an important finding, either way. --- =E[(x-E[x])(y-E[y])] ... Copied to Clipboard!
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