Current Events > people are such morons when it comes to science

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Fam_Fam
12/23/18 8:17:39 AM
#1:


I go on FB, and there's a study that found that marijuana use affected the DNA of children of users, and that more use correlated with larger changes in DNA.

A bunch of people just posted "bullshit", so I asked what issues they had with the methodology of the study, or what evidence they had to the contrary.

The response i got was essentially "A ton of people, including myself, used marijuana and had positive benefits, and it was recommended to us by doctors. Also, all of our children turned out fine".

And I'm like, none of that refutes the study results at all, and none of that is actual evidence of anything that would suggest that the results are wrong. People somehow thing that a story of their amazing kids somehow is evidence that there are no possible side effects, and that scientific evidence is "bullshit" when it doesn't agree with their own narrative (which is based in their "experience" with marijuana, and with no actual scientific evidence).
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glitteringfairy
12/23/18 8:18:46 AM
#2:


People in general are morons
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Kombucha
12/23/18 8:28:49 AM
#3:


I used to think maybe the west was in the process of abandoning the scientific method and all of the great advances that came with the renaissance.

I realized I had been sheltered though and only a portion of the elite really cared about finding the truth. It's almost always been this way- the masses have almost always been fucking morons that prefer convenient hearsay and mysticism. Now that we've democratized speech with the internet it's just becoming even more obvious.

Do you remember when Facebook was university only? Pepperidge farm remembers.

inb4 r/iamverysmart
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teepan95
12/23/18 8:31:04 AM
#4:


glitteringfairy posted...
People in general are morons

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PrettyBoyFloyd
12/23/18 8:32:15 AM
#5:


Honestly I don't know how to do the math to figure out how to break down a Time Continual or create a Wormhole to travel around all of God's creation.
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#6
Post #6 was unavailable or deleted.
CoolBro
12/23/18 8:38:54 AM
#7:


some people who dont go to stem ...they dont understand how research study works
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Dragon239
12/23/18 8:40:17 AM
#8:


Post the study please
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Kombucha
12/23/18 8:40:24 AM
#9:


JACKBUTTMOMMY posted...
Kombucha posted...
I used to think maybe the west was in the process of abandoning the scientific method and all of the great advances that came with the renaissance.

I realized I had been sheltered though and only a portion of the elite really cared about finding the truth. It's almost always been this way- the masses have almost always been fucking morons that prefer convenient hearsay and mysticism. Now that we've democratized speech with the internet it's just becoming even more obvious.

Do you remember when Facebook was university only? Pepperidge farm remembers.

inb4 r/iamverysmart


Ppl who have been to university are often the worst culprits.


Depends on the institution & program, yeah.
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catboy0_0
12/23/18 8:40:43 AM
#10:


yah.. I'm not reading that shit
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DarkRoast
12/23/18 8:40:44 AM
#11:


If this is related to methylation and not mutation rate, the actual significance is debatable.
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HydraSlayer82
12/23/18 8:50:16 AM
#12:


DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.

Yeah, I was going to say changing DNA with on and off switches isnt necessarily good or bad. Plenty of useless code in our DNA.
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Fam_Fam
12/23/18 9:23:21 AM
#13:


also, edit: the study was about the fertility and DNA of the men themselves, not their children. it said it was inconclusive if these mutations were passed on.

https://tinyurl.com/ycae4wg9
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COVxy
12/23/18 9:27:05 AM
#14:


DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.


This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.
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Banana_Cyanide
12/23/18 10:00:48 AM
#15:


COVxy posted...
This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.

Wait, you are an MD right?
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NameMeWhatever
12/23/18 10:19:34 AM
#16:


Science is stupid made up bullshit worst than religion anyway, so who cares.
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HydraSlayer82
12/23/18 10:20:57 AM
#17:


NameMeWhatever posted...
Science is stupid made up bullshit worst than religion anyway, so who cares.

7 karma
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Gafemage
12/23/18 10:36:42 AM
#18:


NameMeWhatever posted...
Science is stupid made up bullshit worst than religion anyway, so who cares.


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NameMeWhatever
12/23/18 10:39:01 AM
#19:


HydraSlayer82 posted...
NameMeWhatever posted...
Science is stupid made up bullshit worst than religion anyway, so who cares.

7 karma


This isn't Reddit you plebian. How many "points" you have doesn't matter, it just shows you how much of your life you wasted.

Science is the religion of man. It is putting your faith in man to tell you how the world around you works. Which is just as bad as putting your faith into a magical creator.
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Banana_Cyanide
12/23/18 10:40:54 AM
#20:


You're a special kind of edgy boi aren't you?
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soulunison2
12/23/18 10:43:53 AM
#21:


NameMeWhatever posted...
HydraSlayer82 posted...
NameMeWhatever posted...
Science is stupid made up bullshit worst than religion anyway, so who cares.

7 karma


This isn't Reddit you plebian. How many "points" you have doesn't matter, it just shows you how much of your life you wasted.

Science is the religion of man. It is putting your faith in man to tell you how the world around you works. Which is just as bad as putting your faith into a magical creator.


Holy shit how sheltered are you

Have you ever been shot at
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Kombucha
12/23/18 10:45:25 AM
#22:


soulunison2 posted...
NameMeWhatever posted...
HydraSlayer82 posted...
NameMeWhatever posted...
Science is stupid made up bullshit worst than religion anyway, so who cares.

7 karma


This isn't Reddit you plebian. How many "points" you have doesn't matter, it just shows you how much of your life you wasted.

Science is the religion of man. It is putting your faith in man to tell you how the world around you works. Which is just as bad as putting your faith into a magical creator.


Holy shit how sheltered are you

Have you ever been shot in the head


ftfy
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MrPeppers
12/23/18 10:46:33 AM
#23:


The worst are college-educated individuals who know how to google studies and read abstracts, but aren't versed enough in analyzing the literature to actually parse through what's supportive and what's probably not supportive.

I honestly had no clue how to analyze a study until I was forced to through postgraduate training, and I suspect that most people with just undergraduate degrees have no clue what they're doing.
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soulunison2
12/23/18 10:55:10 AM
#24:


MrPeppers posted...
The worst are college-educated individuals who know how to google studies and read abstracts, but aren't versed enough in analyzing the literature to actually parse through what's supportive and what's probably not supportive.

I honestly had no clue how to analyze a study until I was forced to through postgraduate training, and I suspect that most people with just undergraduate degrees have no clue what they're doing.


oh damn proudclad he's taking shots at you
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COVxy
12/23/18 10:58:38 AM
#25:


Banana_Cyanide posted...
COVxy posted...
This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.

Wait, you are an MD right?


Naw.
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Banana_Cyanide
12/23/18 11:05:01 AM
#26:


COVxy posted...
Naw.

I know someone on here is an MD but I can't remember who it is.
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COVxy
12/23/18 11:06:46 AM
#27:


Banana_Cyanide posted...
COVxy posted...
Naw.

I know someone on here is an MD but I can't remember who it is.


CoffeeBeanz is, which is who I was talking too.

I'm in biomedical sciences broadly, but I'm finishing up my PhD in neuroscience.
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MrPeppers
12/23/18 11:07:06 AM
#28:


Banana_Cyanide posted...
COVxy posted...
Naw.

I know someone on here is an MD but I can't remember who it is.


DarkRoast is an MD with training in internal medicine. COVxy is a PhD in neuroscience.
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COVxy
12/23/18 11:16:28 AM
#29:


MrPeppers posted...
The worst are college-educated individuals who know how to google studies and read abstracts, but aren't versed enough in analyzing the literature to actually parse through what's supportive and what's probably not supportive.

I honestly had no clue how to analyze a study until I was forced to through postgraduate training, and I suspect that most people with just undergraduate degrees have no clue what they're doing.


Also, this is absolutely accurate. Unless the undergrad has had extensive training in a lab, which usually they haven't. It takes a couple of years before an undergrad trained in my current lab is reading the papers with any form of critical lens.
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Banana_Cyanide
12/23/18 11:17:50 AM
#30:


COVxy posted...
CoffeeBeanz is, which is who I was talking too.

I'm in biomedical sciences broadly, but I'm finishing up my PhD in neuroscience.

I just looked up the account and apparently it's closed.
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Gafemage
12/23/18 11:19:30 AM
#31:


Banana_Cyanide posted...
COVxy posted...
CoffeeBeanz is, which is who I was talking too.

I'm in biomedical sciences broadly, but I'm finishing up my PhD in neuroscience.

I just looked up the account and apparently it's closed.

DarkRoast = CoffeeBeanz
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COVxy
12/23/18 11:19:36 AM
#32:


Banana_Cyanide posted...
COVxy posted...
CoffeeBeanz is, which is who I was talking too.

I'm in biomedical sciences broadly, but I'm finishing up my PhD in neuroscience.

I just looked up the account and apparently it's closed.


Yeah, she closed it and opened DarkRoast, afaik.
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Banana_Cyanide
12/23/18 11:21:46 AM
#33:


Gafemage posted...
DarkRoast = CoffeeBeanz

That explains it.

Well I tagged who I needed to so I'll know who to listen to in future topics.
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DarkRoast
12/23/18 11:27:26 AM
#34:


COVxy posted...
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.


This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.


Cool rebuttal

Asshole attitude not called for

Here's my source:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020004/

How epialleles arise in nature is still an open question but environmentally induced epigenetic changes are rarely transgenerationally inherited, let alone adaptive, even in plants. Thus, although much attention has been drawn to the potential implications of transgenerational inheritance for human health, so far there is little support.

Your turn.
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COVxy
12/23/18 11:32:31 AM
#35:


DarkRoast posted...
COVxy posted...
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.


This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.


Cool rebuttal

Asshole attitude not called for


A metric fuckton of biological function is mediated by methylation.

Histone methylation is necessary for the formation of new memories. Synaptic maintenance in general.

Seems incredibly silly, almost ill informed, to wave off methylation effects because they aren't direct mutations lol.
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DarkRoast
12/23/18 11:34:25 AM
#36:


COVxy posted...
DarkRoast posted...
COVxy posted...
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.


This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.


Cool rebuttal

Asshole attitude not called for


A metric fuckton of biological function is mediated by methylation.

Histone methylation is necessary for the formation of new memories. Synaptic maintenance in general.

Seems incredibly silly, almost ill informed, to wave off methylation effects because they aren't direct mutations lol.


No, it isn't.

As evidenced in my thing called a "source"

Epigenetics is a highly debated field with not much good data one way or another. Hence "debatable". Hence you're being a pedantic asshole for seemingly no reason.
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ThePieReborn
12/23/18 11:35:11 AM
#37:


People are morons when it comes to everything.
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COVxy
12/23/18 11:38:16 AM
#38:


DarkRoast posted...
COVxy posted...
DarkRoast posted...
COVxy posted...
DarkRoast posted...
If this is related to methylation and not mutation rate, the actual significance is debatable.


This is pretty fucking stupid coming from an MD. I was writing up a response but couldn't even finish.


Cool rebuttal

Asshole attitude not called for


A metric fuckton of biological function is mediated by methylation.

Histone methylation is necessary for the formation of new memories. Synaptic maintenance in general.

Seems incredibly silly, almost ill informed, to wave off methylation effects because they aren't direct mutations lol.


No, it isn't.

As evidenced in my thing called a "source"


Jesus fuck.

The point wasn't regarding inheritance, there's a shit ton of biological pathways where drug use can affect off spring, you know. So the only one running off about necessity of inheritance of epigenetic effects is you.

The OP referenced observed effects in the children, and you stated that if it's just methylation and not mutation, not necessarily something to write home about. Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes. I only know in depth about brain related ones, by my guess is that any system that depends on the regulation of protein production (which should be just about all of them) is going to heavily depend on methylation.
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DarkRoast
12/23/18 11:39:26 AM
#39:


Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes.

And the impact of this on offspring is hotly debated.

Which is why I said "it's debatable".

Quit arguing in circles just because you're so hot and bothered.
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COVxy
12/23/18 11:40:09 AM
#40:


DarkRoast posted...
Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes.

And the impact of this on offspring is hotly debated.

Which is why I said "it's debatable".

Quit arguing in circles just because you're so hot and bothered.


This is about observed effects in children, not parents...
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Kombucha
12/23/18 11:40:35 AM
#41:


wow i bet these nerds don't even blaze it how are they supposed to science the thc
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Turtlebread
12/23/18 11:42:27 AM
#42:


science works in mysterious ways
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DarkRoast
12/23/18 11:43:09 AM
#43:


COVxy posted...
DarkRoast posted...
Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes.

And the impact of this on offspring is hotly debated.

Which is why I said "it's debatable".

Quit arguing in circles just because you're so hot and bothered.


This is about observed effects in children, not parents...


Really? You sure know a lot about the article that TC hasn't even shown.
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COVxy
12/23/18 11:44:02 AM
#44:


DarkRoast posted...
Really? You sure know a lot about the article that TC hasn't even shown.


I'm responding to the same information as you, which is:

Fam_Fam posted...
study that found that marijuana use affected the DNA of children of users, and that more use correlated with larger changes in DNA.


Regardless as to what the study ACTUALLY says, your comment was silly.
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Fam_Fam
12/23/18 11:44:15 AM
#45:


DarkRoast posted...
COVxy posted...
DarkRoast posted...
Which is crazy from a biological standpoint since methylation is necessary for a large number of biological processes.

And the impact of this on offspring is hotly debated.

Which is why I said "it's debatable".

Quit arguing in circles just because you're so hot and bothered.


This is about observed effects in children, not parents...


Really? You sure know a lot about the article that TC hasn't even shown.


i did post it, post 13. and made a correction about what the findings actually were
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DarkRoast
12/23/18 11:45:19 AM
#46:


COVxy posted...
DarkRoast posted...
Really? You sure know a lot about the article that TC hasn't even shown.


I'm responding to the same information as you, which is:

Fam_Fam posted...
study that found that marijuana use affected the DNA of children of users, and that more use correlated with larger changes in DNA.


Regardless as to what the study ACTUALLY says, your comment was silly.


It's not clear if they're referring to in utero use or post-birth exposure.
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rikasa
12/23/18 11:46:18 AM
#47:


I'm sure that marijuana is way worse than most people realize but stoners don't want to hear the truth
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DarkRoast
12/23/18 11:47:27 AM
#48:


Here's his article:

https://www.dailymail.co.uk/health/article-6512173/Scientists-discover-cannabis-alters-DNA-sperm.html?ito=social-facebook

In the first study of its kind, sperm samples were taken from healthy men - aged 18-to-40 - who claimed to use cannabis at least once a week for the past six months.

These samples were compared against the sperm of 12 men who had not used cannabis in the past six months and had used it a maximum of ten times throughout their lives. Urine samples confirmed their marijuana use.

Results supported past findings that cannabis users have significantly lower sperm concentrations than non-users

When the DNA of the participants' sperm was analysed, the researchers found cannabis is linked to genetic changes.

And the higher the amount of THC in the men's urine, the stronger the changes of carrying mutations were.

It is unclear whether these changes influence a man's fertility or get passed on to his children - the affected sperm may not even be healthy enough to fertilise an egg.



I'm not exactly impressed.

They're also implying point mutations, it seems. Not epigenetics.
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DaveTheUseless
12/23/18 11:48:11 AM
#49:


Uhm pretty sure the world was created in 6 days
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COVxy
12/23/18 11:48:21 AM
#50:


DarkRoast posted...
It's not clear if they're referring to in utero use or post-birth exposure.


That doesn't really matter, if they observed effects of gene methylation in children it would indeed be potentially an important finding, either way.
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