LogFAQs > #914306376

Without spoiling names, the most important Confidants (off the top of my head) are:

Moon, Sun, Fortune, Death, Strength, Temperance, Hierophant, Tower, Star, and of course the party members. Dialogue choices made during most Confidants will have an effect on how much they like you, which can make it easier to rank up to the next rank. There will be a visual indicator when you give a "correct" dialogue response. The personas you have with you will also help rank up a Confidant faster, so you should generally try to have a Persona with the same Arcana as the Confidant you're seeing.

Hierophant can only go up to either rank 3 before completing the 4th Palace's story arc. Again without spoiling anything, it should be obvious when exactly you'll be able to advance it again.

Aside from one specific Moon event, Moon and Sun Confidants will rank up whenever you meet with them. Strength, and any other story related Confidant, will rank up at the same rate no matter what you say.

Don't waste time slots on exercising at home or at the gym, all you'll get out of it is some extra HP and SP.

Buy plant fertilizer and give it to the plant in your room every couple of weeks, you'll get free Kindness points that way. The more expensive the better.

Dungeon wise, don't get too attached to any one persona during casual play. Keep 'em varied to deal with a variety of scenarios and fuse often. This is one of the easier Persona games on Normal Mode, so as long as you're not a complete dingus at JRPGs you should be fine.

Since this is your first playthrough, don't stress too much about doing everything you possibly can. Just do whatever interests you and have fun with it.

Almost forgot, make sure to enable Thieves' Guild. You can use it to see how other players spend their days and see the correct answers to questions in class. There is literally no reason to not have it enabled.
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