She actually inquired about Professor Layton. I am only worried that there will be plenty of puzzles that will frustrate her to the point of destroying property and/or quitting (I'm looking at those games where you have to rearrange blocks so that one object moves from one end to the other).
Otherwise it would be the clear-cut #1 choice. Right now I am considering (in no order):
1. de Blob 2
2. Kirby Mass Attack
3. Kirby Superstar Ultra
4. Professor Layton title (probably will be the one coming out soon)
5. Okamiden
6. Legendary Starfy
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"Anybody interested in grabbing a couple of burgers and hittin' the cemetery?" -Royal
"Oh sure, walk to the sun"- Guybrush