LogFAQs > #961937039

Claire and Leon are actually fairly different aside from the RCPD. And the game actually streamlines the RCPD a bit if you've already played the other campaign.

Unfortunately, you made the same mistake I did by playing Leon first. The game gives you different handguns depending if you've played that character's scenario first or second. Well, more accurately, it gives you both but they use different ammo and all of the lootable ammo is for the second gun. Claire's second handgun is fucking awful.