LogFAQs > #947431281

Its all RNG unfortunately

the only manipulation possible is by exploiting the fact that the first room you choose will never have the satyr sack, so if you want to ensure you get that reward for your run before getting the possible sack/fountain heal for any future room choices

like for example I once used my first choice on a Dionysus boon so that I could ensure I get strong drink before finding the sack/fountain, for a full heal before the boss fight

or even just to make sure you get the extra coin room or centaur heart before getting the sack/heal, etc