How about Star Ocean's Fol, which is accepted in all cultures on all planets, including ones that have no contact with or even concept of life on other worlds.
I think it's suggested multiple times in 1 and 2 that all of the civilizations and intelligent races in the galaxy were seeded by some ancient proto civilization (presumably Nede). Though some of the stuff about how the Expelians were decended from the Nedeians got buried in some obscure PAs/endings, most notably one of Bowman's endings where he finally translated the ancient text that you fetched earlier in the game yet never came up in the story again and discovers that it was actually about the history of Nede. And then while I don't think it's explicitly stated it's also implied that Earth is related to the Nedeians as well (Nede is super blatantly supposed to be Eden, which humans were chased out of by god's angels because they acquired forbidden knowledge. It kind of got fudged in the localization for obvious reasons though.)
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The only certain death in the universe is Mother Hitton's Littul Kittons. Not changing this line until I beat Seven Heroes (2/24/07) - Fulfilled 2/20/18