LogFAQs > #878012714

All right, so I re-watched the trailers and here is my take on what's happening.

The video in the OP shows what happens after the end of Prometheus. David learns of human compassion through Shaw and gains a new appreciation for them. While she is in cryosleep, he learns the ways of the Engineers and their apparent habit of committing mass genocide on worlds that do not develop as they see fit. He knows, from the first film, that they intended to wipe out all the humans on Earth. Wanting to prevent the destruction of humanity, he arrives at the Engineer home world unleashes their own weapon on them.

Now, this is when the other trailer begins:

https://www.youtube.com/watch?v=svnAD0TApb8

This trailer seems to take place on the same Engineer home world, where the new crew is attempting to start a colony. Why that world or how they found it? Don't know yet. However, David's actions have apparently wiped out all traces of animal life. In the part where they find the derelict, we can see them find David (or Shaw's) tags, so we know it's the same one. The biggest reveal, at 1:56, we can see thousands/millions of slaughtered Engineers (or whatever their people are called) in the same city circle from the end of the trailer with David.

Looks like the rest of the film is them dealing with whatever aliens are left who wiped out the Engineer race.
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- The Admiral