House isn't meant to be a Holmes adaptation though. It's inspired by it, but hey Hercule Poirot was inspired by Holmes and he's about as far off from Holmes as you can be outside "he's smart." Can't really call it a bastardization of Holmes when he isn't meant to be him.
Now, you want a bastardization of Holmes? Look no further.
"A case of evil":
SHERLOCK IS A PLAYA