I deleted the Uncharted 3 thing before trying it in the other room. When I brought it back, I tried it my room and it worked fine again.
I think the lesson I take away here is: Uncharted 3 ruins PS3's, and the only way to fix them is by getting anything UC3 out of it.
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You beat yourself up with your past. Don't blame yourself, blame the world. Blame God. Blame me.