Granted, I played the game first, but yeah, unless you have never heard of the game or seen the box, it's not really a spoilery problem. Plus spoilers, pssh, I can handle spoilers.
I've specifically avoided the game because I've heard both the game and anime were good, and I like going into things blind! I actually didn't see this coming for sure early on, though there was plenty of foreshadowing that made me suspicious.
I guess I'll watch it when I get off work because I'm pretty sure I know what it entails now. >_>
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KrahenProphet and Kana are on opposite ends of the Awesome Spectrum.