Lurker > rivers

planets album when

Borderline sanpaku eyes, swipe at own risk!

Hornswoggled posted...

Unless they wanna kick Detroit when it's down, I might be fine.

Detroit is probably a pretty high priority target, given its manufacturing capacity, its proximity to Canada and the Great Lakes, and the high population in the metro area. To be safe in Michigan, best bet is the UP, IMO.

In a mutually assured destruction scenario, living near a big city and being unprepared, I wouldn't die immediately, but it would be very hard times.
I've thought about moving to the interior Pacific Northwest for years, in part because of the relative insulation the terrain, remoteness, and agriculture offer from radiation, people who want your stuff, and starvation.

My jaw
It's not turborecessed but it's underdeveloped enough to give me sleep apnea that probably started shortly after onset of puberty

Antifar posted...

Update:
https://twitter.com/TheM_L_G/status/1493312334873378823

A reminder that Ukraine's president's previous job was playing the president on a Ukrainian sitcom.

o i am laffin

Drank two or three for years
Unfortunately, my sleep is a lot better without it, and even one cup in the morning can mess me up for a couple of nights
I've found the smaller amount in tea OK but I avoid it too

yeah, it's pretty awesome

no wtf

people i don't like

I don't know, what's a duckbear with you?

on youtube i've rented la confidential for $3.99 and bill and ted 3 (terrible) for $5.99
i do paid rentals quite a bit but mostly on apple tv and google play

change the channel marge

EffectAndCause posted...

Zendaya > Both

sheesh

won't watch lol
will read children of hrin though

good luck!

should be an unknown

Yeah that's pretty flipping weird dude

not mostly
just enough to transfer key hard won adaptations to life in europe and north as\ia
mixed species peeps prob shared hundreds of thousands of years of accumulated wisdom, traditions and languages, now all forgotten, ruining any competitive advantage the first eurasians enjoyed
RIP

urbit

no way, not a chance

Wordle 228 5/6






damn

No. Every day I thank God that I'm alive

Questionmarktarius posted...

I donated to nobody, yet still dogpiled with Trump spam.

i get spam for most major candidates in big american elections and sometimes from abroad, probably because because the local-part of my email is a pretty common name

I'd so love to be smart that I'd be willing to pay a surgeon a million dollars to perform osteotomies on my cranial sutures and administer experimental neurotrophic factors and gene therapy

damn, RIP

here's the modern french pronunciation https://commons.wikimedia.org/w/index.php?title=File%3AFr-propre.ogg
the old french pronunciation was probably similar, aside from the r, which would have been a trill back then frfr

only if her name is jack dorsey

nice place
vaulted ceilings are a must

damn, RIP

Thanks
Was going to drive there on Thursday but will delay

CervusCanadensi posted...

Awesome man. What made you make the change? How are HDL and LDL levels? I get routine blood work done too

cool, tracking something in particular, perhaps in a similar kind of experiment, or just trying to stay ahead of the curve?

Total cholesterol right now is 189, HDL 50 (up from 36), LDL 99. That's a pretty typical TC for me; however, although my HDL is up in the short term, it used to average around 90, and LDL more like 70. Some context here is that I'm about 20 pounds heavier than I was for most of those blood tests, presumably that's why my trigs (now declining) were elevated coming into this, so I expect the recent reversal to continue as I shed fat. In fact, until the last week or so, since starting this diet, I've been averaging around 3000 kcals/day, and I haven't been very active. I wanted to prevent weight loss in the beginning in order to prevent that from influencing initial results. I didn't gain any weight despite eating too much. That's not to say everyone would have the same experience.

As far why I started. Short version: felt like crap for a long time even though I was relatively young and lean. Discovered I had sleep apnea a year ago, couldn't tolerate CPAP, got surgery to expand nasal aperture, finally succeeded with CPAP, and started to have more energy and get by without caffeine, but some issues lingered. Signs pointed to biological stress. Went on high-carb, high-sugar diet to reduce stress, with the island of Kitava, Walter Kempner, and Ray Peat as key influences.
Way too long version: well, a little fat loss is a goal, although I'm actually pretty lean and could have done just by eating less on any diet. Basically, I've been interested in health and fitness for a long time, and until recently only had short-term blips of success. I had to limit exercise to once or twice a week or I'd start to feel like crap and not recover between sessions. I had high blood pressure at the doctor's office and at work, but not at home--in fact, at home it was common for me to have low blood pressure, but only while lying down. (This is normal now: 120/75 across positions and heart rate doesn't elevate when standing.) On blood tests, everything usually looked good, although my TSH was usually close to 4--not high enough to be considered hypothyroidism by the general criteria, but it always stood out to me, especially because I had low energy (too low "for me" compared to how I was right before this started in my teens) and cold hands. The median is around 1.5. The other thing that stood out is DHEA-S, which was above the normal range every single time I measured it, regardless of diet. DHEA-S is a marker of biological stress; relevant to the OP, it's an adrenal hormone. This month, for the first time, it was in the middle of the normal range.
I'd known for a while that carbohydrate, especially in the form of sucrose, is anti-stress (Ray Peat), and that high carb diets can be healthy long term (e.g. see the Kitavans, or for an extreme example the work of Walter Kempner, who pioneered the Rice Diet). I benefited from adding carbs, but I never got my carbohydrate:fat ratio much above the typical diet, and I never felt comfortable adding sugar, despite accepting Ray Peat's points. It's just so antithetical to what I've been taught.
Addressing sleep apnea over the last year was huge, but not enough. I finally started getting stronger, but plateaued quickly. I'm still really thin despite the fat I have to lose (visceral), so it's not as if I've exhausted newbie gains. Having tried everything else was what it took to push me to this anti-stress diet, and so far I'm loving it. Starting to gain again and I can work out more often, presumably because I'm no longer constantly catabolic and can actually store glycogen in my muscles.
Looking back, my issues started as a teenager, right around the time my subjective sleep quality started to suffer. My doctor thinks my sleep apnea kicked off all the way back then due to structural changes associated with puberty, and I think it's the long-term damage of undetected sleep apnea that has necessitated an unusual diet.

I'm approaching two months on a diet high in carbohydrate (>80%) with plenty of added sugar. I've done bloodwork twice during this experiment. My blood glucose has been in the low 80s (mg/dl), HbA1c 5%, and triglycerides declining. Also, my TSH has gone from an average of well over 3 down to 1.1, by far the lowest I've ever recorded in over 10 years of testing, rendering my cold hands and feet a thing of the past after 20 years of dealing with them. Even walking outside in sub-zero (F) weather, I swear it feels about 30 degrees warmer to me.
So, I feel pretty good about sugar.
Caffeine is interesting to me. I think that for most people, in moderate amounts, it can be a good thing, and this in part because of its slightly toxic properties. Hormesis.
Unfortunately, I have definitely noticed that I do better without it, including getting more complete sleep starting two or three nights nights after giving it up. I used to consume it very liberally, in part motivated by the fact that I have a fast caffeine metabolism genotype (high CYP1A2 activity). But it turns out that the primary metabolite of caffeine, paraxanthine, which has similar effects to caffeine, itself is metabolized mostly (about two thirds) by a different enzyme, 2A6, which I do not produce at all because of a rare genetic variant. So, my 1A2 has to do the double duty of breaking down caffeine and its byproduct, which may extend the quarter life of systemic effects of caffeine consumption to days.
My 2A6 genotype with effectively zero activity of the enzyme is rare, but there is a minority with reduced activity who probably also shouldn't be taking caffeine very often. I suspect low 2A6 activity is disproportionately high in people who become very enthusiastic about caffeine avoidance.

Variants of CYP2A6 are usually explored for their relationship to smoking. People with low activity of the enzyme are less likely to smoke cigarettes and find it easier to quit because they convert less nicotine to cotinine, its psychoactive byproduct. In my case, I convert none. When I found that out it really made sense: I had experimented with Swedish tobacco, nicotine gum, and vaping in the past, and never felt anything from it.

nice work

Wordle 221 4/6






for a moment thought i'd get it on the second line ah well

Ratchetrockon posted...

started taking finasteride just in case despite not knowing anyone in my family being bald.

great choice, good luck
i first noticed miniaturization going on in my hairline when i was 18, and as it progressed for close to another 18 years, i somehow convinced myself it was settling every step of the way. four months into consistently using fin, i only wish i'd started sooner

i'v elistened to skyrim music, especially atmospheres, probably thousands of hours over the last several years
only played a few minutes of the game though

Didn't endorse, at least not in the clip
a bad thing that is better than another bad thing is still bad

SydneySweenHero posted...

The average age on CE is like 45, so no lol

Even 45-year-olds were eligible for the draft towards the end of WWI
The day before a man's 45th birthday was the cutoff in WWII though
With the amount of medical deferrals today's draftable population would have, in a major war, they'd probably resort to raising the limit to 60, giving test, HGH and experimental injections of youthful blood to late middle age soldiers

you mean i couldve been paid/?

rented 6j after mana, didn't like it. tried again after ct, liked it a lot

i don't have to imagine
i won't do what you tell me

not risking the wellbeing of my immortal soul over that