LogFAQs > #980116707

I think there are only two things that really contradict the games, but I haven't played NV myself, so maybe I've missed something.

One is that there's a date of a major event which contradicts the events of NV pretty hard, but it's not the first time a series has fucked up a timeline by accident and I think there's some possible ambiguity as to what happened in that year.

The other is that ghouls just don't work that way. In the show, they all need a special drug to keep them from going feral. In the games, they can go for centuries and be fine, it's just luck of the draw.