I think I would actually put my two-weeks notice in at work instead of just quitting. My boss is pretty cool and it would be kind of a dick move to just leave, considering there are only 4 people in my department aside from my boss and the 4 of us have been buying tickets together.
After that, I would definitely share it with my family and my pre-winnings friends. That's a hell of a lot of money and certainly wouldn't need all of it.
I've never been much of the charitable type, not that I haven't given to charity or anything, and I don't consider myself stingy, but I tend to spread my charity among the people I'm closest to. I'd probably give some money to some wildlife fund, though.
Once I finally quit work, I wouldn't blow it all on some lame sports team dream, but I would definitely buy some awesome custom-made home, probably near mountains and then I'd spend most of my time learning the ancient art of bison charming.
Oh, and I would fund Suikoden VI.
--
"Filthy lawbreaker, unhand that vending machine!" - Casey Jones