LogFAQs > #961666360

kateee posted...

Planning to get my booster this week.

I read some stuff saying that it's safe to get a different brand than your first time but are there any benefits to doing so, barring obvious things like allergic reactions and whatnot.

There was a study that suggested that a Moderna third dose is somewhat more effective (regardless of which vaccine you got initially), though I believe that was with a full dose for the booster (in practice in the US the Moderna booster is a half dose). That same study found that 3x Moderna was somewhat more effective than 2x Moderna + Pfizer booster. Its pretty unambiguous that an mRNA booster is more effective than a J&J booster regardless of what you got initially (Im not even sure if J&J boosters are approved?)