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TopicNew variant in Tokyo 'EEK'
CobraGT
04/04/21 6:14:03 PM
#11:


from Miami Herald article

"
Dr. David Andrews, a UM pathologist who is leading the universitys study on COVID virus mutations, said his team has noticed a significant increase in lineages carrying the E484K mutation as it examines more versions of the variants.
Rather than focusing their concern on a particular lineage, such as the P1 Brazilian variant, Andrews says his team is now keeping their eyes on the Eek mutation and how it crops up in various places. He noted that the mutation has been tagging along with the U.K. variant, first observed in the United Kingdom, and, more recently, in Oregon.
I think that is something that is going to be concerning in terms of public health, and is going to change the conversation a little bit away from a particular lineage, Andrews said.

Andrew Pekosz, professor of molecular microbiology and immunology at Johns Hopkins Universitys Bloomberg School of Public Health, said he agreed that the E484K mutation was beginning to pop up in viruses of very different backgrounds, as if all the viruses in the world have figured out that this is going to help them.
Now, we have to figure out why its going to help them, Pekosz said. ... Its no longer a variant that were worrying about. Its any virus out there that is picking up the E484K mutation.
Bill Hanage, an epidemiologist at Harvard Universitys T.H. Chan School of Public Health, noted that its not just how often researchers are finding the Eek mutation, but where they are finding it.

It has been popping up all over the place in locations where there has been substantial transmission recently, together with a history of many previous infections, Hanage said, a phenomenon he attributed to some degree of immune evasion.

It is turning up everywhere, and getting more common through the ability to reinfect people who have recovered from their first bout with the virus. While the characteristics of such reinfections in comparison with the first round are not clear, they are obviously worth taking seriously.

"

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