LogFAQs > #933064941

Heart depends who it's with.
Done it with Silent and Defect. Did it on first or second run with Defect, the name of the game is orb spam. Beating the heart easily means 3 key things:

1) DPS
2) Minimal card usage or a lot of block (you take 1 damage every card played)
3) Strength reduction

Easiest run for it?
Get that ? Option where you trade half your life for 5 intangible cards on a Silent poison deck. With a couple Catalysts poison will blow through the heart and anything else with ease. You won't be fighting it for more than 6 turns most likely. Bear in mind the most damage you can do a turn is 300 so you're guaranteed to fight for 4 turns anyway. A shiv deck is possible but needs a loooot of block for the amount of spamming you're gonna do and if you ran into that act 3 boss who limits turn actions your run is probably ending there anyway. If poison ain't happening, Caltrops spam is great too, he's got an x12 attack with a low Strength modifier so you can get 0x12 easy, making for a hilarious result when you've 15 thorns on you. But it'll be longer and you can't fully rely on this.

Defect will take a bit more time usually but it'll be maxing out orbs asap, stacking focus boosts, and a lot of lightning with occasional dark.

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The King Wang.
Listen up Urinal Cake. I already have something that tells me if I'm too drunk when I pee on it: My friends. - Colbert.