I did. It's pretty awesome. Somewhere between Borderlands and Fallout 3, minus all the levelling up and stuff.
Playing on nightmare difficulty, which feels like I'm playing on normal really. I got the Anarchy Edition though, so I'm wearing the Crimson Elite armour, which may be making things easier, but eh, I figure, I paid extra for the extra stuff, so I'm gonna use it.
That said, the trip through the Dead City was pretty intense at times. ****ing mutant zombie things coming out of the ****ing walls, ceilings and floors...
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Still the number one reason for the success of the Internet.