Nice to see Professor Layton and the Unwound Future made the list (I personally would've placed it higher, but I would not have been surprised if it were absent from the list).
I was surprised to see Twilight Princess only placed at #39, as well.
There are several games between 30 and 20 that I don't think very highly of, and would probably not have included had I made my own list, such as Limbo.
I expect Mass Effect 2 to place first, based on some of IGN's other features, though Super Mario Galaxy would be my choice.
Also, I found it amusing that this list seems to be limited to games on seventh gen consoles, even though other games that were released from 200 to now are just as "modern" as many games on the list.
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Ya ain't in Mrs. Quitter's School for Resettin' Babies no more. It's time ya graduated, kid.