Reprogram - there are ways to utilize Reprogram, like a claw deck with Hyperbeam, Hologram and the other 0 cost cards. I just can never risk my focus being garbage. Even if you have something like Orange Pellets to clear the debuff, the most focus you're going to be at is neutral. If this card was like Fasting and gave 3-4 str/dex then that would be a different story.
Thunder Strike - It's probably okay with Snecko Eye. If I'm channeling like 15 lightning to make this card worth it, I'm probably going to be able to kill some other way.
Blizzard - ditto for Blizzard.
Overclock - Ironclad has cards like this but he can also Exhaust them or play something like Fire Breathing/Evolve to benefit from them. For burns, you'd probably need a recycle. Defect is bad with card draw but even with that I'd rather grab a Skim or a Compile Driver or an FTL if you need it to be 0 energy.
Hello World - I talked about this earlier. This card's pretty useful when you're coming up to the first elite, but by the time you're into act 2 it's basically a curse or it's clogging up your deck with mediocre cards.