Extra points if you have to fight your former friends/allies
bully
Oh that's kind of cheap though, you totally know that the kids bad and is going to be the boss. If that is the case basically every Rockatar game ever made
Bully - Your friends at Bullsworth turn on you GTA3 -Im pretty sure that chick turns on you GTASA - Big Smoke is the final boss and your whole hood gets burnt down. You team up with the "pigs" Red Dead Redemption - Your old gang The Warriors - Everyone comes to a truce and then Cyrus is shot. Dozens of other gangs think The Warriors did it.
The Warriors is an excellent example. All the gangs tend to respect their turf and the meeting is getting them together to take down the establishment. One gang shoots Cyrus and everyone thinks its the warriors. The whole game is fighting everyone... Police, Gangs, and everyone else to make it out of the city alive and prove your gangs innocents