From: Panthera | #208
You can create a coherent character by mixing Paragon and Renegade (and ME2 will reward you by making you not be able to do cool things)
Just finished a playthrough where I tried to be as neutral as possible, and I can attest to this!
I think more people die if you go neutral than if you go pure Paragon or pure Renegade because those highlighted options often prevent a lot of people from getting killed!
Well, maybe not pure Renegade if you use the trigger commands because a lot of those involve killing people.
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"Stay with me until the end. Please."
"Not until the end. Always."