It's pretty easy all things considered. If you beat it on normal you should breeze through Professional since you already know what to expect pretty much.
RE5 Professional is actually harder thanks to Uroboros Sprays.
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If you wake up at a different time, in a different place, could you wake up as a different person? [HERO'S PLUNGE]
http://img.imgcake.com/finegifdy.gif