Lurker > r0xm2n

Mao (Disgaea 3). An Overlord tier demon with an EQ (Evil Quotient) of 1.8Million. He's an actual mad scientist. Obliterates the universe in a bad ending too
Tomoyo (Clannad). Very smart, and freakishly powerful (juggling opponents in the air Chun-Li style is EZ for her).
Kazami Yuuji (Grisaia series). Far stronger and resilient then he looks. On one hand, can single handedly slaughter a bunch of hardened terrorists. On the other hand, devises some interesting plans to help his female friends move beyond their psychological problems.
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This has been another (probably) uselessly informative post, by me. Booyah!
http://www.youtube.com/user/MrEvilbyte

Clannad / Almost every ending, and a number of scenes in the After Story. Too many moments to mention...
Planetarian / Just before the ending. If you wern't already crying when she was gunned down, you will when her memories start playing
Grisaia no Kajitsu / Sachi's Ending. The 2nd time I ever cried in a game. Dat Musicbox

Runner ups
Persona 4 / That hospital scene. No one wants to see a kid suffer like that
Grisaia no Kajitsu / A certain hospital scene. The first time I cried in a game, I was utterly destroyed emotionally. It detailed the un named's girl's final moments, before she became Michiru's other personality. After the accident, she was completely paralyzed, but could still see and stare at the ceiling. She couldn't do anything, or communicate with her parents in anyway :(

Yeah, some visual novels can be emotionally devastating....
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This has been another (probably) uselessly informative post, by me. Booyah!
http://www.youtube.com/user/MrEvilbyte

Nominate: Lethal Chef
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This has been another (probably) uselessly informative post, by me. Booyah!
http://www.youtube.com/user/MrEvilbyte