Depends on what intel we have about the Empire's intentions and how much time we have to react. (How fast does a Death Star even travel? Lol)
The ability to blow up a whole goddam planet is grave enough that I think the sacrifices would be a tragic necessity, granted that we knew the Empire was going to use that power anytime soon.
Ideally I'd prefer rebel bases to start getting moved off inhabited planets and stage rescue attempts for as long we could afford before an innocent civilization gets caught in the crosshairs.