LANL publishes a report on preliminary findings of COVID-19 mutations

... They study this from the end goal stance of a working vaccine.

https://www.biorxiv.org/content/10.1101/2020.04.29.069054v1.full.pdf

Key points
Europe had its own strain
US has its own strain
Wuhan had its own strain
There is question as to whether a vaccine would work across strains and if the virus mutates too quickly to make an effective vaccine
Its a highly mutable virus.

Anyway not super great news, that's just my 2 cents directly from the first few pages of the source itself, read it for yourself and make of it what you will. I have only read the first few pages.

Any medical experts want to weigh in?

Now when will it mutate to give me super powers? I smell a new manga series in the future.

From where I stand, the outlook has always been grim regarding a vaccine. There has never been a vaccine for coronavirus. The ones tried for SARS caused the immune system to overreact to the actual virus and the test subjects died. Another recent viral vaccine attempt, swine flu, has a checkered history and has done far more harm than good.

If the virus really mutates as fast as they say to the point where not even natural immunity is possible, I don't see how they can do anything other than a shittier version of the flu vaccine where they just try to guess which strains will be most widespread throughout a region during each season.

They will most likely end up going with something that's never been done before and pushing past most safety regulations, as well as having no liability levied against them during this time of dire need. So maybe we all end up sterile or struck down by aggressive cancer or even dead in 5-10 years. That's not a good look for something that's going to be mandatory to rejoin society.

A vaccine will work for the majority of the strains

Arcanine2009 posted...

A vaccine will work for the majority of the strains

Is this your take from the article?

There wont be a vaccine, only treatments after you get infected. Or eventually most of the population will be walking around infected and with no symptoms.

Ultima Dragon posted...

There has never been a vaccine for coronavirus.

Ultima Dragon posted...

flu vaccine

god damn your post is tinfoil nonsense

P4wn4g3 posted...

Is this your take from the article?

he is talking out his ass ignore him

Bananana posted...

god damn your post is tinfoil nonsense

He's the same poster who was trying to cause fear and said we should all start cutting back to one meal a day now before we are forced to because of food shortages. He just takes real concerns and amplifies them by a million either intentionally to scare people or because he doesn't know what he is talking about.

There is a very real possibility one single vaccine will work across the globe, but there doesn't seem to be a doubt that we can protect enough people for it to not be a major concern.

• high mutation rate in the spike protein, commonly considered best target for vaccine, is concerning.
• mutation rate has the potential to drop off if there is a seasonal drop in cases, since less infections = less mutations. its foolish to declare that because flu fluctuates seasonally then covid will too.
• speculation that antibodies targeting spike protein might have a quick/short active phase, would actually increase severity of infection since a strong immune response with a weak antibody would sidetrack better alternatives.
• early virus from wuhan is being replaced by a virus with a mutation to spike protein at rapid rate.
• worry that recombination of viral genome is taking place and speeding the mutation rate. this happens when a patient becomes infected with two or more distinct strains of the virus, as the viruses infect cells they're able to share genetic material. suggestion that this is happening in areas with weaker sheltering restrictions.

Bananana posted...

god damn your post is tinfoil nonsense

I don't know if they are a crazy person or not, but you didn't point out anything crazy they said.

Influenza and Coronavirus are entirely different classes of viral contagions and he is not mistaken that there has never been a particularly successful vaccine for a coronavirus. He does fail to mention that it is also likely because they tend to burn themselves out before needing annual or widespread vaccination like Influenza.

realnifty1 posted...

I don't know if they are a crazy person or not, but you didn't point out anything crazy they said.

Well for one

The ones tried for SARS caused the immune system to overreact to the actual virus and the test subjects died.

Is absolute bullshit