Current Events > Are antihistamines dangerous?

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BignutzisBack
08/19/19 4:25:26 PM
#1:


They help with allergies of course but I hear they have nasty side effects

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s0nicfan
08/19/19 4:26:38 PM
#2:


IIRC they're hell on your liver with prolonged use.
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BignutzisBack
08/19/19 7:31:05 PM
#3:


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DarkRoast
08/19/19 7:58:37 PM
#4:


I assume you're talking about the allergy antihistamines and not the stomach antihistamines.

The answer is that it's dependent on the generation of the antihistamine, generation 1 antihistamines like diphenhydramine and hydroxyzine are stronger but have more anticholinergic side effects. Generation 2, like cetrizine and loratadine, are weaker but have less side effects.
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MasterGakke
08/19/19 8:04:04 PM
#5:


I don't know if dangerous is the right term, but they're definitely not good for prolonged use. If you take them for a long time you get what's called "rebound congestion" which is you being congested for no reason unless you take the drugs, and the drugs get less and less effective.
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smoliske
08/19/19 8:23:08 PM
#6:


MasterGakke posted...
I don't know if dangerous is the right term, but they're definitely not good for prolonged use. If you take them for a long time you get what's called "rebound congestion" which is you being congested for no reason unless you take the drugs, and the drugs get less and less effective.


antihistamines != decongestants
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DarkRoast
08/19/19 9:10:32 PM
#7:


MasterGakke posted...
I don't know if dangerous is the right term, but they're definitely not good for prolonged use. If you take them for a long time you get what's called "rebound congestion" which is you being congested for no reason unless you take the drugs, and the drugs get less and less effective.


No, you're thinking of decongestants. Antihistamines do not cause rebound congestion.
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BignutzisBack
08/19/19 9:11:14 PM
#8:


DarkRoast posted...
I assume you're talking about the allergy antihistamines and not the stomach antihistamines.

The answer is that it's dependent on the generation of the antihistamine, generation 1 antihistamines like diphenhydramine and hydroxyzine are stronger but have more anticholinergic side effects. Generation 2, like cetrizine and loratadine, are weaker but have less side effects.


what about third generation

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runuts27
08/19/19 9:13:01 PM
#9:


They make you sleepy that's about it.

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DarkRoast
08/19/19 9:13:32 PM
#10:


BignutzisBack posted...
DarkRoast posted...
I assume you're talking about the allergy antihistamines and not the stomach antihistamines.

The answer is that it's dependent on the generation of the antihistamine, generation 1 antihistamines like diphenhydramine and hydroxyzine are stronger but have more anticholinergic side effects. Generation 2, like cetrizine and loratadine, are weaker but have less side effects.


what about third generation


Those are mostly derivatives of second-generation drugs. Levocetirizine (Xyzal) is just an isomer of Cetrizine (Zyrtec) for example
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MasterGakke
08/19/19 9:24:37 PM
#11:


LOL this is exactly what I'm not allowed to give medical advice.
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_Matchabuu_
08/19/19 11:09:21 PM
#12:


DarkRoast posted...
I assume you're talking about the allergy antihistamines and not the stomach antihistamines.

The answer is that it's dependent on the generation of the antihistamine, generation 1 antihistamines like diphenhydramine and hydroxyzine are stronger but have more anticholinergic side effects. Generation 2, like cetrizine and loratadine, are weaker but have less side effects.

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furb
08/19/19 11:10:14 PM
#13:


I have allergy issues. I take one everyday.

Benadryls knock me out. I won't take it..

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