Rugrats
Spongebob
Avatar
Ren & Stimpy
Rugrats and Spongebob are locks. Straight up.
Avatar probably deserves the spot for being a successful anime on Nickelodeon of all places.
Last spot is a toss-up between Ren & Stimpy and Fairly Oddparents. Giving it to the former but I can be talked into changing my mind.
Someday, I too will become Florida Man.