Garioshi posted...
There's probably enough ammo in the game to kill everything twice.
The same could be said of RE3, not to mention you can make even more ammo, including explosive rounds and extra-damage shotgun shells amongst others. You have a more action-oriented dodge prompt, and Jill is a lot more proactive in fighting Nemesis than the previous game's proto-run at the concept with Mr. X. Even if you don't take advantage of electrocuting him, blowing him up in a gas explosion, or just shoulder-tackling him off a bridge, you can defeat Nemesis every time you encounter him, and the game incentives you to do with with even more powerful weapons and healing items that normally can't be acquired elseways.
And if you really want to feel the horror, you can play in Easy mode and be given a damn assault rifle from the jump. But even on Normal you're a walking arsenal.