Only doing platformers so no LoZ/FF/DQ sorry - Results (38 votes)
Castlevania (1986)
21.05%
(8 votes)
8
Contra (1988)
5.26%
(2 votes)
2
Ghosts 'n Goblins (1986)
0%
(0 votes)
0
Mega Man (1987)
7.89%
(3 votes)
3
Ninja Gaiden (1988)
7.89%
(3 votes)
3
Super Mario Bros. (1985)
55.26%
(21 votes)
21
Teenage Mutant Ninja Turtles (1989)
2.63%
(1 vote)
1
Kinda cheating with a few of these since some of them arent really the first in the series (SMB/Ninja Gaiden) and many originated in the arcade rather than the NES, but I think its safe to say the NES was where these series solidified themselves as industry mainstays.