Slay the Spire is kinda tough tbh

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KajeI posted...
My biggest tip for new players is to ALWAYS prioritize taking as little damage as possible every single turn.

That is pretty bad advice. That is especially bad advice if you have any form of sustain, or prior to ascension 5 since you heal full after boss fights. Obviously you aren't intentionally trying to take damage (usually), but prioritizing other cards plays is often far better. Health is a resource, so use it.

My suggestion: Build around what you have and what you know you will be facing. Don't get a specific archetype or deck size in mind; adjust as you go. Don't be afraid to skip card rewards, but don't be afraid to build a big also.