I don't think Spidey has the mental fortitude to take on the Joker, Poison Ivy, or Scarecrow. They're just not his cup of tea.
But Bats wouldn't have any fun with Venom or Morlun. It's be a neat match with Doc Oct or the Green Goblin though
"All I have is my balls and my word, and I don't break them for anyone!"-Tony Montana