I would check your memory usage during those times. I had a massive memory leak on my computer due to corrupted network drivers so that I was pretty much at 95% memory usage all the time while gaming, which caused exactly what you are talking about. Once I fixed that (and doubled the memory on my PC since it was cheap and I never maxed it out when I built it), that fixed all the problems.
Edit: Also, just to be clear, updating corrupted drivers doesn't fix the issue, you have to uninstall and reinstall them. Updating just adds new files on top of the corrupted ones.
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